Symbol
Name
ID

Irf1
interferon regulatory factor 1
MGI:96590

Phenotype annotations related to hematopoietic system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

hematopoietic system phenotype

abnormal T cell proliferation

abnormal thymus cell ratio

increased double-positive T cell number

increased B-1 B cell number

decreased NK cell number

abnormal T cell number

increased T-helper 2 cell number

increased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

abnormal T cell morphology

abnormal splenocyte morphology

abnormal lymphocyte physiology

abnormal immunoglobulin level

impaired natural killer cell mediated cytotoxicity

abnormal macrophage physiology

Availability

Mouse Genotype

Irf1^M1Btlr/Irf1^M1Btlr

Irf1^m2Btlr/Irf1^m2Btlr

Irf1^M3Btlr/Irf1^M3Btlr

Irf1^tm1Cwe/Irf1^tm1Cwe

Irf1^tm1Mak/Irf1^tm1Mak

Irf1^M1Btlr/Irf1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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